Not sure what you should be working on?
The Plan My Week button, found at the bottom of the To Do screen sidebar.
The Plan My Week button looks at your Scheduled Items and plans your week, accounting for deadlines and time available.
If you do not like the week that has been automatically planned you have 30 seconds to click the undo schedule button.
If your Scheduled sidebar is empty, then you are free to populate your To Do list however you see fit.
Items that you have been assigned to will show up in the My Items sidebar once they are in Play.